Natalie and Tom have been best friends forever, but Tom wants them to be much more. When Natalie's longtime boyfriend walks out on her just when she thinks he's going to propose, Tom offers her a different and wildly romantic proposition. He suggests that they spend twenty-six weekends together, indulging in twenty-six different activities from A to Z, and at the end of that time Tom's convinced they'll be madly in love. Natalie, however, is not so sure.

As Natalie's touring the alphabet with Tom, her mother's going through her own romantic crisis—while Tom's unhappily married sister-in-law, Lucy, struggles with temptation. And over the course of six amazing months, three generations of passionate dreamers are going to discover that, no matter how clever they are, love—and life—is never as easy as A, B, C . . .